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Industrial Microbiology and Biomanufacturing (3)
BAE 425/525
(SPRING SEMESTER)
Mondays, Wednesdays and Fridays, 9.10 – 10.00 a.m., 143 Weaver Labs
Instructor: Ratna Sharma, Assistant Professor
Office: 280 Weaver Labs
Phone: 515-6746
email: ratna_sharma@ncsu.edu

This course caters to the needs of agricultural, biological, and food engineers, at the undergraduate and graduate level, who are interested in the basics and real world application of bioprocessing but lack in depth microbiological knowledge.

Course Pre-requisites:
MB 351 or graduate standing

Text Book:

Industrial Microbiology: An Introduction by M. K. Waites, N. L. Morgan, J. S. Rockey, and G. Higton. 2001. Blackwell Science Ltd.

Reference Books:

•    Bioprocess Engineering Basic Concepts by M. L. Shuler and F. Kargi. 2002. 2nd edition. Prentice Hall, Inc.
•    Biochemical Engineering Fundamentals by J. E. Bailey and D. F. Ollis. 1986. 2nd edition. McGraw-Hill, Inc.

BAE 25:
•    Journals that cover articles on bioprocess engineering and industrial microbiology such as (but not limited to):
•    Biotechnology and Bioengineering
•    Applied Biochemistry and Biotechnology
•    Applied and Environmental Science

Topic areas:

•    Microbial cell structure and function
•    Microbial growth and nutrition
•    Microbial metabolism

•    Industrial microbes
•    Fermentation media and preparation
•    Fermentation systems
•    Downstream processing

•    Microbial enzymes: kinetics, applications, production
•    Fuels and industrial chemicals
•    Pharmaceuticals
•    Food and beverage fermentation: beer, wine
•    Food additives and supplements
•    Microbial biomass production
•    Environmental biotechnology
•    Microbial biodeterioration and control
•    Animal and plant cell culture
•    Product development, regulations and safety

•    Emerging applications

Course policies:


•    Homeworks will be assigned on Wednesdays and will be due the following Wednesday
•    There will be two in class exams and a final exam, with questions focusing on the learning outcomes/course objectives of the class.
•    To obtain graduate credit students will have to actively participate in one hour of journal club discussion per week and prepare a project proposal
•    Discussion papers should be handed over to the group at least a week before presentation
•    If there is sufficient enthusiasm a visit to a brewery will be organized!!!


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